The ACOT8 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to hACTE-III, and hTE. This antibody recognizes Human, Mouse, and Rat antigen. The ACOT8 Antibody has been validated for the following applications: Immunofluorescence, and Western Blot.
Description
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs By similarity. May be involved in the metabolic regulation of peroxisome proliferation.Watanabe H., Biochem. Biophys. Res. Commun. 238:234-239(1997).Liu L.X., J. Biol. Chem. 272:13779-13785(1997).Jones J.M., J. Biol. Chem. 274:9216-9223(1999)